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Tuesday, 25 April 2017 07:16

SC Elections 2017

Some positions of the SC will be vacant this year. The election will take place during the annual meeting in Milan in September 2017. The deadline for application is September 1st [except for the position of Nontuberculous Mycobacteria (August 1st)] The application form can be downloaded here.
Wednesday, 25 January 2017 10:21

TBnet Academy 2017

The 3-Day TB Academy in Armenia was a great succes!
Wednesday, 25 January 2017 08:14

MDR TB Symposium

    Registration kindly requested by email until February 20th 2017: Mrs. Cordula Ehlers TBnet office Research Center Borstel cehlers@fz-borstel.de       
Wednesday, 12 July 2017 06:01

TBnet Meeting 2017

Dear TBnet members, the TBnet meeting in 2017 will take place in Milan on September 8th
Thursday, 15 September 2016 07:40

CURE OF MDR-TB

The Tuberculosis Network Clinical Trialsgroup (TBnet), an international consortium of clinicians and scientists, has proposed new treatment outcome definitions for MDR-TB. TBnet documented the management of patients with MDR-TB at 23 different sites across Europe where they found that treatment outcomes according to the definitions proposed by the WHO did not correlate to sustained culture conversion and being free of relapse in the absence of therapy. Applying the novel TBnet MDR-TB outcome criteria “cure” is reached twice as often as compared to the WHO criteria in their study.
Tuesday, 08 March 2016 11:01

Ongoing Projects

  TBnet #16 A database for paediatric tuberculosis in Europe Principal investigator: Beate Kampmann (UK) This study was facilitated by the award of the TBnet Grant 2010. The project started in October 2010. The data-base will include (1) demographic characteristics (2) information about active TB and Microbiology (3) LTB (4)Follow-up (5) children with TB contact but not treated and (6) adverse events of treatment.  TBnet #34 / NTM-NET #5 Treatment of M. xenopi infections (CaMoMy Trial) Principal Investigator: Claire Andrejak The main objective of this study is to determine the 6-months sputum conversion rate with a clarithromycin- or moxifloxacin-containing regimen in patients with a M. xenopi pulmonary infection. This study is originally located and facilitated in France, other European centers are now asked to participate. TBnet #39 Differentiation of antigen-specific T-cells in pulmonary tuberculosis Principal Investigator: Barbara Kalsdorf (Germany) This study aims to characterize the immunophenotype and function of peripheral blood and BAL-derived Mycobacterium (M.) tuberculosis specific T-cells in suspects of tuberculosis to identify whether expansion of antigen-specific T-cells occurs only at a central compartment (lymph nodes) or in addition, at the site of the infection. We will identify the phenotype of unstimulated and antigen-specific T-cells in blood and BAL for the ability to relocate (CD3, CD4, CD8, CD27, CD45RO, CCR7) and to replicate at the site of infection (CD25, IL-2, Ki67). Early apoptosis markers like Annexin V will be used on blood and BAL-cells to investigate whether the local activation of M. tuberculosis-specific CD4 /CD8 T-cells induces protection against cell death in the course of acute pulmonary infection. TBnet #52 Management of tuberculosis in transplant recipients, Principal Investigator: Martina Sester (Germany) Influence of screening for tuberculosis on tuberculosis incidence after organ transplantation in regions of tuberculosis incidence of <40/100000   INSTRUCTION (version 02.12.2015) STUDY PROTOCOL (version 02.12.2015) TBnet FORM (version 02.12.2015) TBnet #53 TBnet-DM Study. Socio-demographic and clinical characteristics of patients with Tuberculosis and Diabetes in Europe Principal Investigator: Enrico Girardi (Italy) This study aims to describe the epidemiology, and clinical presentation of  tuberculosis in patients with diabetes in Europe. Specific objectives are: 1.To determine the prevalence of DM among TB patients  in Europe with special reference to possible differences among different countries and between autochthonous and migrant patients. 2. To analyze epidemiological and demographic variables associated with DM among TB patients. 3. To describe clinical presentation  of TB-DM and diagnosis of DM in TB patients  Protocol and Appendix can be found here (only for members).   TBnet #54 Performance of a new generation IGRA in immunocompromised individuals, Principal Investigator: Martina Sester (Germany)    
Tuesday, 08 March 2016 09:58

Photo Contest 2016

INFORMATION: THE PRIZE WILL NOT BE AWARDED THIS YEAR - PLEASE APPLY AGAIN IN 2017     TBnet called for a photograph related to TB for a photoexhibition and book. Submit your images of TB by March 24th 2016 to cehlers@fz-borstel.de. You can submit up to three pictures.           EVALUATION ON PROGRESS   Submission details Participation in the TBnet photoproject is free to all (you do not have to be a TBnet member, but you can sign up anyway, membership is free)   Submit up to 3 photos (jpeg, tif, png or similar, >300 dpi preferred), a title and a description (<200 words) related to TB   Photos cannot be submitted previously to a photo contest   Submission deadlinefor photos and accompanying material is March 24th 2016   Photos, title and text should be submitted electronically together with the details of the photographer and a copyright transfer agreement to Cordula Ehlers in the TBnet office at cehlers@fz-borstel.de   Consent forms(if applicable) must be signed by all individuals that can be identified on the photos prior to submission. Consent forms must be kept with the photographer   Photos will be judged by an international jury   The photographer of the best image will be awarded   Members of the TBnet steering committee and office are not eligible for the award   THANK YOU FOR YOUR PARTICIPATION   FORMS              
Monday, 11 January 2016 11:14

11th TBnet Meeting

      Our 11th TBnet meeting took place on September 2nd in London, United Kingdom. Thanks a lot to our local host, Graham Bothamley! Report will follow.  
Monday, 29 September 2014 09:28

TBnet Academy

  The 3rd TBnet Academy took place in Chisinau / Moldova from May 4th to 6th 2015 Deadline for application was: February 20th 2015 Application process closed. The program can be found here. Report here.          TBnet ACADEMY 2015   FREE FELLOWSHIP GRANTS     What it is about:   3 Day Tuberculosis Academy especially for residents, fellows, doctoral students and post-docs. A forum for young clinicians and researchers in the field of tuberculosis to exchange ideas and to learn from each other under expert guidance and mentorship.   Where: Chisinau, Rep. of Moldova   When: May 03 (arrival) – May 07 (Departure) 2015     The program includes:   Keynote lectures on: Collaborative TB research in Europe Emerging tuberculosis drug-resistance Pediatric tuberculosis Non-tuberculous mycobacteria infections     Reviews (provided by participants) on: Immunology Microbiology Molecular biology Epidemiology Public Health Clinical management of TB   Special features:  How to plan a research project How to get funded How to write a manuscript How to give a winning presentation Clinical pearls Hot topics on the international research agenda     Faculty:   Sofia Alexandru (Rep. of Moldova) Victor Botnaru (Rep. of Moldova) Dumitru Chesov (Rep. of Moldova) Valeriu Crudu (Rep. of Moldova) Liliana Domente (Rep. of Moldova) Josè Dominguez (Spain) Rodica Gramma (Rep. of Moldova) Lorenzo Guglielmetti (France) Constantin Iavorschi (Rep. of Moldova) Valeriu Istrati (Rep. of Moldova) Beate Kampmann (UK) Christoph Lange (Germany) Ekatarina Norok (Rep. of Moldova) Elena Romancenco (Rep. of Moldova) Morten Ruhwald (Denmark) Doina Rusu (Rep. of Moldova) Claudia Schacht (Germany) Martina Sester (Germany) Timo Ulrichs (Germany) Valentina Vilc (Rep. of Moldova) Dirk Wagner (Germany)     Coordination committee:   Prof. Rodica Gramma (USMF, Moldova) Ass. Prof. Dumitru Chesov (USMF, Moldova) Prof. Christoph Lange (Research Center Borstel, Germany) TBnet secretariate: Mrs. Cordula Ehlers (cehlers@fz-borstel.de)