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Based on an increasing interest for the new immunodiagnostic tools used to detect the infection with Mycobacterium tuberculosis, to treat Latent Tuberculosis Infection (LTBI) and to prevent tuberculosis (TB) reactivation in immunocompromised/healthy individuals, the project gathered a self-organized group of pulmonologists, epidemiologists, specialists in infectious diseases at the end of August 2006 in Copenhagen. The Copenhagen meeting was organized with the contribution of the coordinators of the EUROSIDA project in order to learn about their infrastructure, coordination, data management and funding procedures. This first meeting was aimed at preparing the agenda for a second meeting to be organized during the 2006 ERS Conference.

During the Munich meeting important issues about the TBnet were discussed, in particular how to establish a European clinical research collaboration on TB related topics. It was decided about a first step producing evidence on priority clinical problems of TB management by sharing retrospective data already collected by the participating centres, or by conducting clinical trials that potentially can reach the stage of an accepted manuscript for publication within one year time. Further, the main interest topics for the network were defined including: Diagnosis, Immunology, Intervention, Surveillance of TB. The idea was to combine them “ad hoc” in order to answer priority clinical questions related to TB management..  

Following these first two meetings, on November 9th and 10th 2006, 41 physicians and colleagues from allied scientific disciplines from 12 European countries gathered at the Research Center Borstel (Germany), to share ideas on relevant research proposals and to built a network for TB research in Europe. After two intense days of discussion on 20 proposals, organization and combination of the main proposals in 6 projects, TBnet has seen light.